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Cover picture: Minimal model of the gating processes in MthK, which involves three conformational equilibria: pH-dependent assembly/disruption of the gating ring (state I and II); Ca2+/pH-dependent gating ring conformational shifts between open and closed states (state II and III), and Ca2+/pH-independent open/closed transitions of the channel pore (state III and IV) (see article by Li et al., 109–120).
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