|
|
|
|
|
|
|
||
Cover picture: Fast-rising calcium sparks of skeletal muscle (left, top two traces) require concerted, near-simultaneous activation of groups of intracellular release channels. Slower events (bottom three traces) propagate sideways, implying sequential channel activation. These different activation modes may involve different ryanodine receptor isoforms (1, blue, or 3, green) at junctional or parajunctional locations (right) (see article by Zhou et al.,301-309).
|
|