About the Cover
Cover picture: alpha-Helical structural elements within the voltage-sensing domains of a K+ channel, as revealed by scanning mutagenesis. The first four transmembrane segments (S1 to S4) are drawn as membrane-spanning alpha-helices (cylinders). Two additional a-helices are shown in the extracellular linkers between the transmembrane segments. A possible arrangement of the transmembrane helices in the tetramer is shown from an extracellular vantage point (right). See related article by Li-Smerin, Y., D.H. Hackos, and K.J. Swartz, in this issue, pp. 33-49.
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