The Journal of General Physiology
Avanti Polar Lipids
  Home | Help | Feedback | Subscriptions | Archive | Search | Table of Contents
This Article
Right arrow PDF (Full Text)
Right arrow Alert me when this article is cited
Right arrow Citation Map
Services
Right arrow Email this article
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new content in the JGP
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via CrossRef
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Parker, J. C.
Right arrow Articles by Castranova, V.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Parker, J. C.
Right arrow Articles by Castranova, V.
Social Bookmarking
Add to CiteULike   Add to Complore   Add to Connotea   Add to Del.icio.us   Add to Digg   Add to Reddit   Add to Technorati  
What's this?

The Journal of General Physiology, Vol 84, 379-401, Copyright © 1984 by The Rockefeller University Press

ARTICLES

Volume-responsive sodium and proton movements in dog red blood cells

JC Parker and V Castranova

Shrinkage of dog red blood cells (RBC) activates a Na transport pathway that is Cl dependent, amiloride sensitive, and capable of conducting Na- proton counterflow. It is possible to establish transmembrane gradients for either Na or protons and to demonstrate that each cation species can drive reciprocal movements of the other. The nature of the coupling between Na and proton movements was investigated using the fluorescent probe diS-C3(5) and also by an indirect method in which K movements through valinomycin channels were used to draw inferences about the membrane potential. No evidence was found to suggest that the Na-proton pathway activated by shrinkage of dog RBC is a conductive one. By exclusion, it is presumed that the coupling between the counterflow of Na and protons is electroneutral. The volume-activated Na-proton fluxes in dog RBC have certain properties that distinguish them from similar transport pathways in other cell types.
Add to CiteULike CiteULike   Add to Complore Complore   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us   Add to Digg Digg   Add to Reddit Reddit   Add to Technorati Technorati    What's this?


This article has been cited by other articles:


Home page
 Am. J. Physiol. Regul. Integr. Comp. Physiol.Home page
A. T. Hanna-Mitchell and E. M. Gebruers
The hydroosmotic response of frog urinary bladder to serosal hypertonicity is dependent on adenylate cyclase for its maintenance and affected by [Cl-]o changes
Am J Physiol Regulatory Integrative Comp Physiol, July 1, 2006; 291(1): R213 - R223.
[Abstract] [Full Text] [PDF]

Home page
 J. Appl. Physiol.Home page
T. A. Heming, G. Boyarsky, D. M. Tuazon, and A. Bidani
pHi responses to osmotic cell shrinkage in the presence of open-system buffers
J Appl Physiol, October 1, 2000; 89(4): 1543 - 1552.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Physiol. Cell Physiol.Home page
Y. Miyata, S. Muto, S. Yanagiba, and Y. Asano
Extracellular Cl- modulates shrinkage-induced activation of Na+/H+ exchanger in rat mesangial cells
Am J Physiol Cell Physiol, June 1, 2000; 278(6): C1218 - C1229.
[Abstract] [Full Text] [PDF]

Home page
 Physiol. Rev.Home page
M. P. Blaustein and W. J. Lederer
Sodium/Calcium Exchange: Its Physiological Implications
Physiol Rev, July 1, 1999; 79(3): 763 - 854.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Physiol. Cell Physiol.Home page
M. O. Bevensee, E. Bashi, W.-R. Schlue, G. Boyarsky, and W. F. Boron
Shrinkage-induced activation of Na+/H+ exchange in rat renal mesangial cells
Am J Physiol Cell Physiol, March 1, 1999; 276(3): C674 - C683.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Physiol. Renal Physiol.Home page
Y. Miyata, Y. Asano, and S. Muto
Hyperosmotic mannitol activates basolateral NHE in proximal tubule from P-glycoprotein null mice
Am J Physiol Renal Physiol, April 1, 2002; 282(4): F718 - F729.
[Abstract] [Full Text] [PDF]


  Home | Help | Feedback | Subscriptions | Archive | Search | Table of Contents