|
|
|
|
|
|
|
||
The Journal of General Physiology, Vol 71, 615-643, Copyright © 1978 by The Rockefeller University Press
ARTICLES |
M Meredith and DG Moulton
Responses of 75 single units in the goldfish olfactory bulb were analyzed in detail for their relationship to the time-course of the change in odor concentration during each odor stimulus. Odor stimuli were controlled for rise time, duration, and peak concentration by an apparatus developed for the purpose. This apparatus enabled aqueous odor stimuli to be interposed into a constant water stream without changes in flow rate. The time-course of the concentration change within the olfactory sac was inferred from conductivity measurements at the incurrent and excurrent nostrils. Temporal patterns of firing rate elicited by stimuli with relatively slow rising and falling phases could be quite complex combinations of excitation and suppression. Different temporal patterns were produced by different substances at a single concentration in most units. Statistical measures of the temporal pattern of response for a small number of cells at a given concentration were more characteristic of the stimulus substance than any of three measures of magnitude of response. The temporal patterns change when the peak concentration, duration, and rise time of the stimuli are varied. The nature of these changes suggests that the different patterns are due primarily to the combined influence of two factors: (a) a stimulus whose concentration varies over time and (b) a relationship between concentration and impulse frequency which varies from unit to unit. Some units produce patterns suggestive of influence by neural events of long time constant. The importance of temporal patterns in odor quality and odor intensity coding is discussed.
CiteULike 
Complore 
Connotea 
Del.icio.us 
Digg 
Reddit 
Technorati What's this?
This article has been cited by other articles:
|
|
 |
|
  A. A. Nikonov and J. Caprio Odorant Specificity of Single Olfactory Bulb Neurons to Amino Acids in the Channel Catfish J Neurophysiol, July 1, 2004; 92(1): 123 - 134. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
R. W. Friedrich and G. Laurent Dynamics of Olfactory Bulb Input and Output Activity During Odor Stimulation in Zebrafish J Neurophysiol, June 1, 2004; 91(6): 2658 - 2669. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 T. K. Alkasab, J. White, and J. S. Kauer A Computational System for Simulating and Analyzing Arrays of Biological and Artificial Chemical Sensors Chem Senses, March 1, 2002; 27(3): 261 - 275. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 R. W. Friedrich and G. Laurent Dynamic Optimization of Odor Representations by Slow Temporal Patterning of Mitral Cell Activity Science, February 2, 2001; 291(5505): 889 - 894. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
D. Mellon Jr. and C. J. Wheeler Coherent Oscillations in Membrane Potential Synchronize Impulse Bursts in Central Olfactory Neurons of the Crayfish J Neurophysiol, March 1, 1999; 81(3): 1231 - 1241. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 G. Laurent, M. Wehr, and H. Davidowitz Temporal Representations of Odors in an Olfactory Network J. Neurosci., June 15, 1996; 16(12): 3837 - 3847. [Abstract] [Full Text] [PDF]
|
|
|
|
