The Journal of General Physiology
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The Journal of General Physiology, Vol 67, 469-474, Copyright © 1976 by The Rockefeller University Press

ARTICLES

Nonuniform distribution of sodium in the rat hepatocyte

G Hooper and DA Dick

The volume of the nucleus, endoplasmic reticulum (including Golgi complex), mitochondria, and cytoplasmic ground substance was measured in rat hepatocytes by stereological methods. The Na content was also measured by flame photometry. Variations in Na content correlated significantly with variations in volume of nucleus and endoplasmic reticulum. From the correlation parameters, Na concentrations were estimated as follows: nucleus, 108 mM; endoplasmic reticulum (ER) (including Golgie complex) 27 mM; cytoplasm (including and remaining organelles) 16 mM.
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