The Journal of General Physiology
Axon Instruments microelectrode amplifiers
  Home | Help | Feedback | Subscriptions | Archive | Search | Table of Contents
This Article
Right arrow Full Text (PDF, 877K)
Right arrow Alert me when this article is cited
Services
Right arrow Email this article
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new content in the JGP
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via CrossRef
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Moreno, J. H.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Moreno, J. H.
Social Bookmarking
Add to CiteULike   Add to Complore   Add to Connotea   Add to Del.icio.us   Add to Digg   Add to Reddit   Add to Technorati  
What's this?

The Journal of General Physiology, Vol 66, 117-128, Copyright © 1975 by The Rockefeller University Press

ARTICLES

Routes of nonelectrolyte permeability in gallbladder. Effects of 2,4,6- triaminopyrimidinium (TAP)

JH Moreno

The organic cation 2,4,6-triaminopyrimidinium (TAP), which blocks the tight junction channels for cation permeability across gallbladder, also inhibits gallbladder permeability (P) to urea and glycerol without significantly affecting P to Cl(-), sucrose, 1,7-heptanediol, or water (osmotic or diffusional permeabilities). These effects together with the comparisons of P's in frog with P's in rabbit gallbladder suggest that sucrose migrates exclusively through the leakage pathway (through where Cl(-) permeates), and that urea and glycerol permeate in addition through both, the tight junction channels for cations and a polar pathway at the cell membranes. Water and 1,7-heptanediol probably permeate mainly through the epithelial cell membranes.
Add to CiteULike CiteULike   Add to Complore Complore   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us   Add to Digg Digg   Add to Reddit Reddit   Add to Technorati Technorati    What's this?


This article has been cited by other articles:


Home page
 JCBHome page
P. J.I. Salas, M. L. Rodriguez, A. L. Viciana, D. E. Vega-Salas, and H.-P. Hauri
The Apical Submembrane Cytoskeleton Participates in the Organization of the Apical Pole in Epithelial Cells
J. Cell Biol., April 21, 1997; 137(2): 359 - 375.
[Abstract] [Full Text] [PDF]


  Home | Help | Feedback | Subscriptions | Archive | Search | Table of Contents