The Journal of General Physiology
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The Journal of General Physiology, Vol 26, 65-73, Copyright © 1942 by The Rockefeller University Press

ARTICLE

INCREASED IRRITABILITY IN NITELLA DUE TO GUANIDINE

W. J. V. Osterhout 1

1 From the Laboratories of The Rockefeller Institute for Medical Research

Guanidine applied to Nitella may lower the threshold of E.M.F. required to produce electrical stimulation and may give rise to trains of action currents. Its effect thus appears to be somewhat similar to that observed in animals.

Rapid action currents are produced as well as "square topped" action curves and transitional forms.

These effects may be due in part to increased protoplasmic conductivity produced by the penetration of guanidine.

Submitted on May 21, 1942


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