¹ From the Physiological Laboratory, Clark University, Worcester

Studies of axon potentials set up by pressure stimuli applied to single cutaneous receptors in frog's skin indicate that the mechanical stimulus excites the free nerve endings directly.

Adaptation to constant pressures or to intermittently applied pressures (failure of the response) may be due to the reduction of excitability of the nerve endings by potassium released under the pressure from surrounding epithelial cells.

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