The Journal of General Physiology, Vol 16, 795-800,
Copyright © 1933 by The Rockefeller University Press
THE DIFFUSION COEFFICIENT OF CRYSTALLINE TRYPSIN
Henry W. Scherp 1
1 From the Laboratories of The Rockefeller Institute for Medical Research
The diffusion coefficient of crystalline trypsin in 0.5 saturated magnesium sulfate at 5°C. is 0.020 ±0.001 cm.2 per day, corresponding to a molecular radius of 2.6 x 107 cm.
The rate of diffusion of the proteolytic activity is the same as that of the protein nitrogen, indicating that these two properties are held together in chemical combination and not in the form of an adsorption complex.
Accepted on March 23, 1933