The Journal of General Physiology
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The Journal of General Physiology, Vol 15, 29-43, Copyright © 1931 by The Rockefeller University Press


ARTICLE

THE PRESENCE OF A GELATIN-LIQUEFYING ENZYME IN CRUDE PEPSIN PREPARATIONS

John H. Northrop 1

1 From the Laboratories of The Rockefeller Institute for Medical Research, Princeton, N. J.

A protein fraction has been isolated from crude pepsin preparations which is about 400 times as active as crystalline pepsin in the lique-faction of gelatin.

The activity as measured by the digestion of casein, edestin or egg albumin is less than that of crystalline pepsin.

It is more resistant to alkali than the crystalline pepsin.

Accepted on June 13, 1931


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